Pathology EMQ

 

Name:  Charlotte Burns

Theme:  Calcium Handling

 

OPTION LIST

 

A

1o Hyperparathyroidism

I

Osteomalacia

B

2o Hyperparathyroidism

J

Osteoporosis

C

3o Hyperparathyroidism

K

PagetŐs Disease

D

Calcitonin

L

Parathyroid Hormone

E

Calcitriol

M

Pseudohypoparathyroidism

F

Cholecalciferol

N

Vitamin D3

G

Ergocalciferol

O

 

H

Hypoparathyroidism

P

 

 

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all. 

 

 

1.  Disorder of calcium handling most commonly seen in patients with end-stage chronic renal failure, in which the plasma calcium is raised. 

 

 

2.  Peptide hormone responsible for increasing plasma calcium in response to reduced levels by stimulating osteoclast activity.

 

 

3.  Form of vitamin D produced following the action of 1α hydroxylase on 25-OH D3 in the kidney.

 

 

4.  Which of the above acts to stimulate 1α hydroxylase activity in the kidney to increase the production of vitamin D3. 

 

 

5.  The diagnosis in a patient with a plasma calcium concentration of 2.8mmol/L (2.2-2.6), a phosphate concentration of 0.76mmol/L (0.8-1.2) and a parathyroid hormone level of 11.2pmol/L (1.3-7.7). 

 

 

ANSWERS

1. C

2. L

3. E

4. L

5. A